This online exhibit under Office of NIH History asks three major questions: (1) How do genes cause disease? (2) Can gene therapy work? (3) How do we manipulate genes and should we? It introduces topics such as genetic basics, diagnosing and treating genetic diseases, gene therapy, the human genome project, and Ethics issues. Abundant images and glossary links used in this exhibit might be...
In this activity, students are exposed to some of the most significant biomolecules currently exploited by technology and identify their natural origins. They also explain the significance of the roles these biomolecules play in nature, as well as for humans. Specifically, students work to develop a logical process for a real-life application of biotechnology (insulin production) using knowledge...
This activity is a case study that draws from the work of Yoshiura et al (2006), where a single base substitution in the ABCC11 gene can result in phenotypic change in earwax consistency. A New York Times article discussing this study is used as the main reading of this activity, as it discusses the case without using key terminology and without specifically explaining the genetics behind the...
This activity is designed to help students with the concepts of mitosis and meiosis. Specifically, the activity is designed to help students learn the different recognized stages of mitosis, differentiate homologous and nonhomologous chromosomes and recognize sister chromatids (duplicated chromosomes). In addition, students complete an activity in which they simulate/model the process of meiosis,...
In this approximately 20 to 25 minute lecture activity, students work collaboratively in groups to learn about the genetic basis of, and molecular mechanisms behind, the variation observed in squirrel coat color. As components of the activity, students will respond in groups to clicker style questions, and will work together to complete a worksheet that, ultimately, requires the construction of a...
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