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Genetics -- Mutations

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View Resource A Revolution In Progress: Human Genetics and Medical Research

This online exhibit under Office of NIH History asks three major questions: (1) How do genes cause disease? (2) Can gene therapy work? (3) How do we manipulate genes and should we? It introduces topics such as genetic basics, diagnosing and treating genetic diseases, gene therapy, the human genome project, and Ethics issues. Abundant images and glossary links used in this exhibit might be...

http://history.nih.gov/exhibits/genetics/index.htm
View Resource Angiogenesis: Cancer

This animation illustrates how a cancer tumor forms in a bed of healthy cells. The animation goes on to show how the tumor recruits blood vessels and how metastasis occurs. A tumor consists of cells that are dividing at an abnormally high rate, crowding surrounding healthy cells and competing for resources. Tumor growth typically proceeds in 3 dimensions, pushing out from the surrounding...

http://www.hhmi.org/biointeractive/media/angiogenesis-lg.mov
View Resource Central Dogma - Genes to Phenotype Teachable Tidbit (The Sciurus Case of the Black Squirrel)

In this approximately 20 to 25 minute lecture activity, students work collaboratively in groups to learn about the genetic basis of, and molecular mechanisms behind, the variation observed in squirrel coat color. As components of the activity, students will respond in groups to clicker style questions, and will work together to complete a worksheet that, ultimately, requires the construction of a...

http://clse-cwis.asc.ohio-state.edu/teachable_tidbits/centra...
View Resource Connecting Concepts: Natural Selection: Topic 2 - The Genetic Basis of Variation

This unit provides three games for students to learn genetic variations and the selective pressure in three different populations (fish, bacteria, flowers). Students will need to select an individual and decide whether the individual has high or low fitness under certain environment. Then students will need to decide whether the change (like mutations of mating) can improve the fitness of that...

http://ats.doit.wisc.edu/biology/ev/ns/t2.htm?
View Resource Cracking the Code of Life, Chapter 14: A Family Disease

Chapter 14 of a 2 hour program. Running time 08:05. Mutations in the BRCA genes increase a woman's chance of having breast cancer and ovarian cancer. Everyone has these genes, but in a few families, these genes have mutations that are inherited. This chapter chronicles the story of three sisters with cancer in their family. Now that tests exist to determine if a person carries the mutated gene,...

http://www.pbs.org/wgbh/nova/genome/program.html
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