This animation visualises research published in Nature Medicine (Vol 15, Issue 8, 2009) by the laboratory of Jane Visvader and Geoffrey Lindeman. The mammary gland is comprised of three main cell types; alveolar, ductal and myoepithelial cells. Stem cells can develop into any of the three cell types through a series of intermediate cell stages. One intermediate is the luminal progenitor cell,...

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This activity was designed for small group discussions during class. The purpose of this activity was to help students see the importance of the cytoskeleton and to get some exposure to mechanisms of cancer, specifically metastasis of cancer cells. The images and much of the information was taken from a review published by Fife, et al., Brit. J. Pharm., 2014. The first page of the file contains...

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In this activity, students will use an HHMI Biointeractive module to review the eukaryotic cell cycle, key players that regulate the cycle, and applications to cancer. The first part of the activity focuses on going through the module and drawing out the key cell cycle regulators on to a figure of the cell cycle. The second part of the recitation has the students interpret a graph depicting the...

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This animation illustrates how breast stem cells respond to steroid hormone despite the cells not having any steroid receptors. The animation illustrates the research published in Nature (Vol 465, Issue 7299, 2010) by the laboratory of Jane Visvader and Geoffrey Lindeman.

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An overview of the human mammary gland with a focus on the role of breast stem cells during pregnancy. The primary function of the mammary gland is to produce milk to nourish young offspring. The mammary gland is comprised of three main cell types; alveolar, ductal and myoepithelial cells. During pregnancy, the mammary gland increases in size due to the action of breast stem cells, which can...

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